Chromosomal Mutations, Genetic Disorders, and Oncogenesis

8 lessons

Goal

Analyze the molecular origins of point mutations, chromosomal aberrations, mutagenic agents, and the multi-step genetic basis of cancer.

Sources of Genetic Variation in Populations

8 lessons

0 of 8 done

Sources of Genetic Variation in PopulationsUp next
Point Mutations: Silent, Missense, and Nonsense MutationsPremiumNot started yet
Frameshift Mutations: Insertions and DeletionsNot started yet
Structural Chromosomal Aberrations: Deletions, Inversions, and TranslocationsNot started yet
Numerical Chromosomal Aberrations: Aneuploidy and PolyploidyNot started yet
Mutagenic Agents: Radiation, Chemical Carcinogens, and Viral MutagensNot started yet
Molecular Basis of Monogenic Disorders: Sickle Cell, Cystic Fibrosis, and Huntington'sNot started yet
The Molecular Basis of Oncogenesis: Proto-Oncogenes and Tumor SuppressorsNot started yet

Standards Covered

Curriculum Framework

8 lessons

Explain the molecular mechanisms of the central dogma, including transcription, RNA processing, translation, and eukaryotic gene regulation.

7 lessons

Solve complex monohybrid, dihybrid, and sex-linked crosses, and interpret pedigrees using Mendelian principles and Morgan's chromosome theory.

8 lessons

Analyze the molecular origins of point mutations, chromosomal aberrations, mutagenic agents, and the multi-step genetic basis of cancer.

8 lessons

Evaluate recombinant DNA techniques, genomics tools, stem cell therapies, cloning, and ethical considerations in biotechnology.

8 lessons

Synthesize evolutionary lines of evidence, quantify allele frequency shifts, model natural selection, and trace hominin phylogeny.

8 lessons

Classify organisms across three domains and major kingdoms using cladistics, dichotomous keys, and structural/life-cycle adaptations.